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Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) Peptide

ALOX5AP Reactivité: Humain Hôte: Lapin BP
N° du produit ABIN2763850

Aperçu rapide pour Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) Peptide (ABIN2763850)

Antigène

ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))

Origine

Humain

Source

  • 4
Lapin

Application

Blocking Peptide (BP)
  • Restrictions

    For Research Use only
  • Stock

    -80 °C
  • Antigène

    ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))

    Sujet

    Seems to be required for the activation of 5-LO (5-lipoxygenase). Could play an essential role in the transfer of arachidonic acid to 5-LO. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes. Genetic variations in FLAP may be a cause of susceptibility to ischemic stroke [MIM:601367], also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.
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